(R)-3-HYDROXYPYRROLIDINE
HYDROCHLORIDE |
PRODUCT
IDENTIFICATION
|
CAS
NO. |
104706-47-0 |
|
EINECS
NO. |
|
FORMULA |
C4H9NO·HCl |
MOL
WT. |
123.58 |
H.S.
CODE
|
|
DERIVATION |
|
SYNONYMS |
(R)-3-Pyrrolidinol
hydrochloride; |
TOXICITY
|
|
CLASSIFICATION
|
|
PHYSICAL
AND CHEMICAL PROPERTIES
|
PHYSICAL
STATE |
yellow
powder
|
MELTING
POINT |
|
BOILING
POINT |
108 - 110 C
at 8 mm Hg |
SPECIFIC
GRAVITY |
1.045 |
SOLUBILITY
IN WATER |
|
pH |
|
VAPOR
DENSITY |
|
AUTOIGNITION
|
|
NFPA
RATINGS
|
Health:
1; Flammability: 0; Reactivity:
0 |
REFRACTIVE
INDEX
|
|
FLASH
POINT |
|
STABILITY |
Stable
under ordinary conditions. Moisture,
light sensitive. |
GENERAL
DESCRIPTION
|
Pyrrolidine
is a part of the structure of amino
acids (proline, hydroxyproline and hygrine). Chiral pyrrolidines are used as
enantiomeric intermediate in developing the asysmmetric single isomeric drugs
including antitumor, anesthetic, antipasmodic, hepatotoxic,
antiinflammatory or anti-HIV activity products. They are useful in preparing pyridone
carboxylic acid antibacterials,
k-receptor opioids,
and optically secondary alcohols. |
SALES
SPECIFICATION |
APPEARANCE
|
yellow
powder
|
CHEMICAL
PURITY
|
99.0%
min |
OPTICAL
ROTATION
|
-6.5°
~ -7.5° (C=3.5 in MeOH) |
TRANSPORTATION |
PACKING |
|
HAZARD
CLASS |
Not
regulated |
UN
NO. |
|
OTHER
INFORMATION |
Hazard Symbols: n/a, Risk Phrases: 36/37/38,
Safety Phrases: 26-37/39 The free
base gives a positive optical rotation (+5.5° ~
+7.5°, C=3.5 in MeOH)). The hydrochloride form has
a
negative optical rotation. |
PRICE |
|
|